(E)-Guggulsterone | CAS:39025-24-6

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(E)-Guggulsterone

CAS No: 39025-24-6
Product Name: (E)-Guggulsterone
Other Name:
(E)-Guggulsterone
(17E)-Pregna-4,17-diene-3,16-dione
(17E)-Pregna-4,17(20)-diene-3,16-dione
Trans-Guggulsterone
Z-Guggulsterone
 
Density: 1.1±0.1 g/cm3
Boiling Point: 463.3±45.0 °C at 760 mmHg
Melting Point: 170-171.5°
Molecular Formula: C21H28O2
Molecular Weight: 312.446
Flash Point: 172.3±25.7 °C
Exact Mass: 312.208923
PSA: 34.14000
LogP: 3.65
Vapour Pressure: 0.0±1.1 mmHg at 25°C
Index of Refraction: 1.557
 
Specification
Appearance: White to off-white powder
Assay: ≥99.0%
Residue on ignition: ≤0.1%
Loss on drying: ≤0.5% 
 
Application
Guggulsterone is a plant steroid found in the resin of the guggul plant, Commiphora mukul. Guggulsterone can exist as either of two stereoisomers, E-guggulsterone and Z-guggulsterone. In humans, it acts as an antagonist of the farnesoid X receptor, which was once believed to result in decreased cholesterol synthesis in the liver. Several studies have been published that indicate no overall reduction in total cholesterol occurs using various dosages of guggulsterone, and levels of low-density lipoprotein ("bad cholesterol") increased in many people. Nevertheless, guggulsterone is an ingredient in many nutritional supplements.
 
Package: 25kg/drum, can also be designed according to customer requirements.
Storage: Store in cool place. Keep container tightly closed in a dry and well-ventilated place.



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