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terbinafine hydrochloride
Terbinafine hydrochloride
(E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethanamine monohydrochloride
Appearance and properties: crystalline powder
Density: 1.007g/cm3
Boiling point: 417.9ºC at 760 mmHg
Melting point: 204-208°C
Flash point: 183.7ºC
Refractive index: 1.586
Storage conditions: -20ºC Freezer
Use:
It is an antifungal drug for the treatment of fungal infections. It is an effective non-competitive inhibitor of squalene epoxidase from Candida with a Ki value of 30 nM.
| Items of Analysis | Standard of Analysis | Test Results |
| Appearance | White or off-white powder | Off-white powder |
| Identity by 1H-NMR (Solvent: Chloroform-d) |
Reference to original data | Conform |
| Purity by HPLC (Area nominalization) |
≥94.0% (A) | 94.15% |
| Melting Point | For information | 200.2~200.6 ℃ |
| Loss on drying | ≤0.50% (w/w) | 0.46% |
| Conclusion | Conforms to Factory Standard | |
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