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Chemical Name:Piperazine-1,4-diethylamine
CAS.NO:6531-38-0
Synonyms:2-[4-(2-Amino-ethyl)-piperazin-1-yl]-ethylamine;2,2′-(1,4-Piperazinediyl)diethanamine;1,4-Piperazinediethanamine;Piperazine-1,4-diethylamine;2,2′-piperazine-1,4-diyldiethanamine
Molecular Formula:C8H20N4
Molecular Weight:172.271
HS Code:2933599090
Physical and Chemical Properties:
Melting point:N/A
Boiling point:302.2±10.0 °C at 760 mmHg
Density:1.0±0.1 g/cm3
Index of Refraction:1.512
PSA:58.52000
Exact Mass:172.168793
LogP:-1.97
Material Safety Information (Applicable for Hazard Chemicals)
RIDADR:UN 1760
Packing Group:II
Contact us for information like 2-[4-(2-Amino-ethyl)-piperazin-1-yl]-ethylamine chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight,2,2′-piperazine-1,4-diyldiethanamine physical properties,toxicity information,customs codes,safety, risk, hazard and MSDS, CAS,cas number,2,2′-piperazine-1,4-diyldiethanamine Use and application,2-[4-(2-Amino-ethyl)-piperazin-1-yl]-ethylamine technical grade,usp/ep/jp grade.
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Currently, there is no bispecific antibody that has same target as IBI321 in clinical-stage development worldwide. Preclinical studies of IBI321 have demonstrated that the combination of these two monoclonal antibodies further enhanced the immune activation with improved convenience of administration.
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TIGIT is highly expressed in gastric cancer. And pre-clinical experiments have proved that synergistically targeting PD-1 and TIGIT could significantly repress gastric tumor growth. We look forward to the clinical results of IBI321, particularly in GI tumors.
Dr. Hui Zhou, Senior Vice President of Clinical Development of Innovent, stated: “By specifically targeting both PD-1 and TIGIT, this type of bispecific antibody is designed to provide synergistic effects by blocking both the PD-1/PD-L1 and TIGIT/CD155 pathways – with the goal of improving the anti-cancer efficacy.
Currently, there is no bispecific antibody that has same target as IBI321 in clinical-stage development worldwide. Preclinical studies of IBI321 have demonstrated that the combination of these two monoclonal antibodies further enhanced the immune activation with improved convenience of administration.
Therefore, the development of an anti-PD-1/TIGIT bispecific antibody has the potential to provide patients with more effective and convenient treatment. We look forward to hope that IBI321 will benefit more patients. 1-acetoxyoct-2-ene manufacturers The development of various enabling technologies has been critical in expanding the potential of biocatalytic processing, as well as in promoting its uptake across the pharmaceutical industry. Carbamic acid, 2-thiazolyl-, 9-methyl-9-azabicyclo[3.3.1]non-3-yl ester suppliers Besides McNamara’s hire, GSK said it’s expected to name a chair for the OTC firm later this year, who will then establish the board. β-IONYL ACETATE vendor & factory.
