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Chemical Name: BOC-L-Proline
CAS.NO:15761-39-4
Synonyms:Boc-L-Proline
N-(tert-Butyloxycarbonyl)-L-proline
N-(tert-Butoxycarbonyl)-L-proline
(S)-1-(tert-Butoxycarbonyl)pyrrolidine-2-carboxylic acid
N-Boc-L-proline
Molecular Formula: C10H17NO4
Molecular Weight:215.24600
Physical and Chemical Properties:
Density: 1.201 g / cm3
Boiling point: 337.2ºC at 760 mmHg
Melting point: 133-136ºC
Flash point: 157.7ºC
Refractive index: 1.503
Specification:
Appearance:White to off-white crystalline powder
Purity:≥99.0%
Specification:A white to off-white crystalline powder
Identification by HPLC:The retention time of major peak in the chromatogram of the sample solution corresponds to that in the chromatogram of the standard solution, as obtained in the purity.
Melting range:Between 132 and 137ºC
Water by K.F.:Not more than 0.5% w/w
Chromatographic purity (%area normalization, by HPLC)
1)Purity
2)Total impurities
:Not less than 99.0% Not more than 1.0%
Packing:
25kg / drum
Storage:Closed, cool and dry place below 0ºC.
Application: It can be used to synthesize Daclatasvir which inhibits the HCV protein NS5A, and thus can be used as a drug candidate for the treatment of hepatitis C (HCV).Intermediates of Daclatasvir CAS:1009119-64-5
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