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Product Description:
Product Name: L(-)-Glutathione CAS NO: 27025-41-8
Synonyms:
Oxiglutatione;
glutathonedisulfide;
glutathione oxidized form;
Chemical & Physical Properties:
Appearance: White lyophilized powder
Assay :≥99.0%
Density: 1.54g/cm3
Boiling Point: 1196.5℃ at 760mmHg
Melting Point: 178-182℃
Flash Point: 677.4℃
Refractive Index: -105 ° (C=2, H2O)
Water Solubility: Soluble
Stability: Stable. Incompatible with strong oxidizing agents.
Storage Condition: 2-8℃
Vapor Pressure: 0mmHg at 25℃
Safety Information:
RTECS: MC0556500
Safety Statements: S24/25
WGK Germany: 2
Risk Statements: R36/37/38
Hazard Code: Xi
Glutathione disulfide (GSSG) is a disulfide derived from two glutathione molecules.
In living cells, glutathione disulfide is reduced into two molecules of glutathione with reducing equivalents from the coenzyme NADPH. This reaction is catalyzed by the enzyme glutathione reductase. Antioxidant enzymes, such as glutathione peroxidases and peroxiredoxins, generate glutathione disulfide during the reduction of peroxides such as hydrogen peroxide (H2O2) and organic hydroperoxides (ROOH):
2 GSH + ROOH → GSSG + ROH + H2O
Other enzymes, such as glutaredoxins, generate glutathione disulfide through thiol-disulfide exchange with protein disulfide bonds or other low molecular mass compounds, such as coenzyme A disulfide or dehydroascorbic acid.
2 GSH + R-S-S-R → GSSG + 2 RSH
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