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Chemical Name:Nafamostat mesilate
CAS No.:82956-11-4
Molecular weight:539.58
Appearance:White crystalline powder
Assay: 98% min
Category: API
- Description
Description
Nafamostat mesilate
Chemical Name:Nafamostatmesilate
CAS No.:82956-11-4
Molecular weight:539.58
Appearance:White crystalline powder
Assay: 98% min
Nafamostat mesilateTypical Properties
| Test Items | Standard specifications | Result | Remarks | |
| Description | White crystalline powder，It is freely soluble in formic acid, soluble in water, and practically insoluble in ethanol (99.5).It dissolves in 0.01 mol/L hydrochloric acid TS. | conform | N/A | |
| Identification | IR corresponds to that of reference standard | conform | IR | |
| Rt corresponds to that of reference standard | conform | HPLC | ||
| pH | 4.7～5.7 | 5.12 | c = 1.0g/100ml in H2O | |
| Clarity and color of solution | the colorless and clear | conform | c = 1.0g/100ml in H2O | |
| Loss on drying (%) | ≤0.5 | 0.13 | 1g | |
| Heavy metals | Not more than 10ppm | conform | 1g | |
| Residue on ignition (%) | ≤0.1 | 0.06 | 1g | |
| Chloride (%) | ≤0.02 | conform | 0.5g | |
| Sulfate (%) | ≤0.008 | conform | 2g | |
| Related substance | Individual impurity(%) | <0.1 | 0.06 | HPLC |
| Totalimpurities (%) | <0.5 | 0.13 | HPLC | |
| Assay（on the anhydrous basis）(%) | 98.5～101.5 | 99.6 | titration | |
| Residual solvents | ||||
| Methanol | Not More Than 3000ppm | conform | GC | |
| Ethanol | Not More Than 5000ppm | conform | GC | |
| Acetone | Not More Than 5000ppm | conform | GC | |
| Pyridine | Not More Than 200ppm | conform | GC |
Nafamostat mesilateUsage
It is used to improve acute pancreatitis, acute exacerbation of chronic pancreatitis, acute pancreatitis after operation, acute pancreatitis after pancreatic ductography and traumatic pancreatitis.
Nafamostat mesilatePackaging and Shipping
Packing:1kg/bag or as your requirements
Delivery:not dangerous goods
Nafamostat mesilateStorage
Store in a cool, dry, dark place.
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82956-11-4 technical grade,usp/ep/jp grade.
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