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Product Description:
Product Name: TAUROURSODEOXYCHOLIC ACID CAS NO: 14605-22-2
Synonyms:
2-[[(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid;
3α,7β-Dihydroxy-5β-cholan-24-oic Acid N-(2-Sulfoethyl)amide Dihydrate;
Chemical & Physical Properties:
Appearance: White solid
Assay :≥99.00%
Density: 1.216 g/cm3
Boiling Point: 496.4℃ at 760mmHg
Melting Point: 173-175℃
Flash Point: 214.2℃
Refractive Index: 46 ° (C=1, EtOH)
Safety Information:
RTECS: KI7372500
Safety Statements: S22; S24/25
WGK Germany: 2
HS Code: 29242990
Tauroursodeoxycholic acid (TUDCA) is an ambiphilic bile acid. It is the taurine conjugate form of ursodeoxycholic acid (UDCA). Humans are found to have trace amounts of TUDCA. However, bears contain large amounts of TUDCA in their bile; UDCA and conjugates comprise about 47% of the bile in American black bears and up to 76% in Asiatic bears. TUDCA has been used in ancient Asian pharmacopoeias for its supposed beneficial effects. UDCA is produced in several countries for the treatment of gallstones and liver cirrhosis. It is not approved by the Food and Drug Administration, in the U.S. while UDCA is approved in the United States for the treatment of primary biliary cirrhosis Ongoing research is finding TUDCA has diminishing apoptotic effects, helping with cardiac function, Huntington”s disease, Parkinson”s Disease, and stroke. Recently, TUDCA has been found to have protective effects in the eye, especially concerning retinal degenerative disorders.
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