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Product Description:
Product Name: Tenofovir CAS NO: 147127-20-6
Synonyms:
(R)-(1-(6-amino-9H-purin-9-yl)propan-2-yloxy)methylphosphonic acid;
Apropovir;
9-Pmpa;
Chemical & Physical Properties:
Appearance: White crystalline solid
Assay :≥99.00%
Density: 1.79 g/cm3
Boiling Point: 616.1℃ at 760 mmHg
Melting Point: 276-280℃
Flash Point: 326.4℃
Water Solubility: 13.4 mg/mL (25℃)
Safety Information:
RTECS: DB8930000
Hazard Class: 8
Safety Statements: S22; S26; S27; S36/37/39
HS Code: 2933990090
WGK Germany: 3
Packing Group: III
RIDADR: UN 3261 8/PG 2
Risk Statement: R34
Hazard Code: C
Microbicides for sexually transmitted diseases are pharmacologic agents and chemical substances that are capable of killing or destroying certain microorganisms that commonly cause human infection (for example, the human immunodeficiency virus).
Microbicides are a diverse group of chemical compounds that exert their activity by a variety of different mechanisms of action. Multiple compounds are being developed and tested for their microbicidal activity in clinical trials. Microbicides can be formulated in various delivery systems including gels, creams, lotions, aerosol sprays, tablets or films (which must be used near the time of sexual intercourse) and sponges and vaginal rings (or other devices that release the active ingredient(s) over a longer period). Some of these agents are being developed for vaginal application, and for rectal use by those engaging in anal sex.
Although there are many approaches to preventing sexually transmitted diseases in general (and HIV in particular), current methods have not been sufficient to halt the spread of these diseases (particularly among women and people in less-developed nations). Sexual abstinence is not a realistic option for women who want to bear children, or who are at risk of sexual violence. In such situations, the use of microbicides could offer both primary protection (in the absence of condoms) and secondary protection (if a condom breaks or slips off during intercourse). It is hoped that microbicides may be safe and effective in reducing the risk of HIV transmission during sexual activity with an infected partner.[full citation needed]
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